منابع مشابه
Ophthalmic Drug Delivery Systems for Antibiotherapy—A Review
The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug delivery approach. Topical eye drops are the most commonly used formulation in ocular drug delivery. Despite the good tolerance for patients, this topical administration is only focus on the anterior ocular diseases and had a high precorneal lo...
متن کاملOphthalmic Drug Delivery in Glaucoma—A Review
Glaucoma is a progressive optic neuropathy and medical therapy is the initial option for the treatment of this potentially blinding condition. Topical instillation of eye drops from the bottle is the most common glaucoma drug delivery form. Due to limited permeability of anterior ocular surface, natural clearance and drainage, eye drops contain large amounts of inactive ingredients. Effective p...
متن کاملAdvances in ophthalmic drug delivery.
Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The use of drug-loaded contact lenses and ocular inserts allows drugs to be better placed where they are needed for more direct delivery. Developm...
متن کاملCurrent Trends for Ophthalmic Drug Delivery: a Review
Controlled and sustained delivery of ophthalmic drugs continues to remain a major focus area in the field of pharmaceutical drug delivery with the emergence of new, more potent drugs and biological response modifiers that may also have very short biological half-lives. The present review was conducted on drug delivery to the ocular route. Polymers with suitable rheological properties can facili...
متن کاملBiodegradable fumarate-based drug-delivery systems for ophthalmic applications.
The function of a photocrosslinked poly(propylene fumarate) (PPF)/poly(N-vinyl pyrrolidone) (PVP) matrix for the sustained release of three ophthalmic model drugs, acetazolamide (AZ), dichlorphenamide (DP), and timolol maleate (TM), was investigated. The drugs differ in molecular weight and degree of dissociation in aqueous environments; both are parameters that significantly influence drug dif...
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ژورنال
عنوان ژورنال: Drug development & registration
سال: 2021
ISSN: 2658-5049,2305-2066
DOI: 10.33380/2305-2066-2021-10-1-57-66